Protein Quality

Physico-chemical characterisation

GlycoThera offers the following arsenal of analytical methods to analyse and assess the identity as well as integrity and quality of the primary structure of proteins:
  • Full protein sequencing (incl. leucine and isoleucine position determination)
  • Amino acid composition analysis
  • Disulfide bond linkage analysis
  • N- and C-terminus integrity analysis
    • Pyroglutamate formation
    • Lysine clipping
  • Methionine oxidation analysis
  • Precise mass determination
  • Analysis for deamidation of Asn and Gln
  • Cysteine stage (e.g. cysteinylation, oxidation)
 
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