Physico-chemical characterisation
GlycoThera offers the following arsenal of analytical methods to analyse and assess the identity as well as integrity and quality of the primary structure of proteins:
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Full protein sequencing (incl. leucine and isoleucine position determination)
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Amino acid composition analysis
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Disulfide bond linkage analysis
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N- and C-terminus integrity analysis
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Pyroglutamate formation
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Lysine clipping
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Methionine oxidation analysis
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Precise mass determination
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Analysis for deamidation of Asn and Gln
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Cysteine stage (e.g. cysteinylation, oxidation)